We are interested in the resident macrophages of the central nervous system, the microglia. We seek to understand the dynamics and functions of microglia during tissue development, in contexts of degeneration or tissue injury, their interactions with other cell types, and their function in regeneration of damaged tissue. We use the zebrafish as our model organism and we apply a variety of approaches to answer our questions, including microscopy, transgenesis, next generation sequencing, and gene targeting.
We are looking for motivated and enthusiastic graduate students and research technicians to join our group! Please contact Dr. Mitchell if you are interested!